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All concentrations were prepared and analyzed in triplicate

Clinical trials (SURPASS for type 2 diabetes and SURMOUNT for obesity) have demonstrated substantial weight reduction in people taking tirzepatide, with weight loss varying by indication, dose, and population

Live imaging of HeLa cells using the RUSH system with epi-fluorescent microscope HeLa cells (RIKEN BioResource Research Center, #RCB0007) were transfected with DNA plasmids encoding Str-KDEL_SBP-mCherry-GPI (gift from Franck Perez, Addgene plasmid # 65295) and EGFP-ST using the Lipofectamine 3000 (Thermo Fisher Scientific) transfection reagent according to the manufacturers instructions

Shots may help reduce or prevent this damage