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Albeit the allostasis-adaptive responses of HPT axis are essential for the proper adjust to critical conditions, they difficult the clinical diagnosis of thyroid diseases, since the hormonal levels that comprise this axis exhibit a wide range of reference values

These mice were developed to model the occurrence of occupational medicamentosa-like dermatitis due to TCE, which is a severe hypersensitivity reaction that occurs after TCE skin contact or inhalation and is associated with both hepatitis and kidney damage besides the characteristic effects on the skin

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