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Yet, the greatest and most lasting results are achieved when medication is combined with positive lifestyle changes
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Statements Author contributions XZ and MW mainly wrote and revised the manuscripts, and constructed the framework of the manuscript

Consistent with these findings, peripherally administered CCK induces cFos immunoreactivity in GLP-1-producing neurons of the hindbrain vagal complex of the NTS [354], and surgical vagal deafferentation reduces CCK-induced NTS neuronal cFos activation by approximately 50% [355]