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This triagonist profile is the subject of ongoing preclinical and clinical research examining synergistic receptor crosstalk effects not observed with single- or dual-agonist compounds

Patients seeking access have two pathways: enrollment in active Phase 3 TRIUMPH clinical trial sites, or beginning treatment with an FDA-approved alternative such as tirzepatide until retatrutide becomes commercially available

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Semaglutide, when used in combination with other medications, may raise the risk of developing low blood sugar levels or hypoglycemia