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Reduced hepatic cholesterol synthesis: Glucagon signaling downregulates HMG-CoA reductase, the same enzyme targeted by statins

Who can benefit from GLP-1 medications

For consumers, it is hard to tell the difference between real medical advice and paid promotion

Heart rate elevation, a theoretical concern with GLP-1 agonists, occurs modestly (24 bpm increase) and does not translate to increased arrhythmias or sudden cardiac events in study populations
