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Optimisation of glycaemic control plays a key role in the prevention of both macro- and micro vascular complications 1 but often results in unwanted weight gain 2 and adverse clinical outcomes

The phase 2 trial included 103 participants who completed both treatment and baseline plus week 36 DEXA scans

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The key warning signs are: Severe, persistent upper abdominal pain that doesn't respond to position changes or over-the-counter remedies Pain radiating to the back this classic pancreatitis presentation distinguishes it from routine GI discomfort Pain accompanied by persistent vomiting that prevents keeping any fluids down Fever combined with abdominal pain suggests an inflammatory or infectious process Published guidelines from the European Association for the Study of Diabetes recommend that GLP-1 receptor agonist treatment should be stopped immediately when pancreatitis is suspected, pending full clinical evaluation