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Description
The relative risks of complications, including progression of CKD to end-stage kidney disease (ESKD), CVD and mortality, are increased with both reduced eGFR and elevated UACR levels [1]
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Acetic acid and butyric acid in SCFAs can activate GPR41 and GPR43 and inhibit histone deacetylase activity to exert anti-inflammatory effects [171]
Diabetes Care 24:489494 Green BD, Irwin N, Duffy NA, Gault VA, OHarte FP, Flatt PR (2006) Inhibition of dipeptidyl peptidase-IV activity by metformin enhances the antidiabetic effects of glucagon-like peptide-1
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