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Description
These drugs do not suppress the immune system the way corticosteroids, methotrexate, or mycophenolate do

Switching from earlier in the week to later This direction is easier

Nausea is the most common side effect, affecting approximately 15-30% of patients depending on the dose, followed by diarrhea (13-16%), vomiting (6-12%), and constipation (6-7%)

Precautions US BOXED WARNING: RISK OF THYROID C-CELL TUMORS: In both male and female rats, this drug causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures