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Here, we identified that DPP4 in hepatocytes but not TEK receptor tyrosine kinasepositive endothelial cells regulates the local bioactivity of incretin hormones and gluconeogenesis

Such heterogeneity combined with multiple histamine receptors, differentially expressed within the hypothalamus and in multiple cell types, contributes to the complexity of the histaminergic system and highlights multiple ways histamine may serve to influence neuronal activity and food intake