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The NHS guidelines recommend you see your healthcare provider if you: Are regularly constipated Are regularly bloated Have blood in your poo Have lost weight without trying Are constipated and tired all the time Are taking medicine that's causing constipation Notice sudden changes in the how you poo (your bowel habits) Have tummy pain SemaPen is a weight loss clinic founded and staffed by obesity treatment experts

Additionally, LY3298176 led to weight loss, with a higher proportion of patients achieving the weight loss targets compared to dulaglutide and the placebo