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For patients experiencing skin sensitivity while taking semaglutide, several management strategies can help minimize discomfort while maintaining therapeutic benefits
2022 AHA/ACC/HFSA guideline for the management of heart failure: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines

Signs include consistently elevated fasting or post-meal blood glucose readings, rising HbA1c above your target (often 48 mmol/mol), return of diabetes symptoms such as increased thirst and frequent urination, or unexplained fatigue