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Tirzepatide While semaglutide works on a single hormone, tirzepatidethe active ingredient in brand-name drugs Mounjaro and Zepboundis a dual-hormone medication, according to Anekwe

It's confusing a temporary, adaptive response with a direct pharmacological side effect

Hypothyroidism can cause muscle aches, tenderness, stiffness, joint pain, and swelling of the small joints of the hands and feet, symptoms that can mimic arthritis, tendinopathy, or chronic pain of undetermined origin

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