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Current evidence suggests that benefitsboth glycemic control and weight reductionare maintained with continued treatment, but discontinuation frequently results in weight regain and worsening of metabolic parameters

How Many People Experience Semaglutide Side Effects Large-scale clinical trials tracked thousands of people taking semaglutide for weight loss and type 2 diabetes

What Research Shows About GLP-1 Therapy and Thyroid Health Clinical trials of semaglutide (SUSTAIN and LEADER trials) and tirzepatide (SUMO and SURPASS trials) did not identify direct thyroid toxicity or unexpected interactions with levothyroxine