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Cryo-EM structure of the retatrutide-bound human GLP-1R-Gs complex

RR 0.51, P<0.001), cerebrovascular disease (RR 0.50, P<0.001), and heart failure (RR 0.55, P<0.001)

Age-appropriate dosing, comorbidity assessment, and genetic predisposition screening can support safer, more personalized treatment conversations
