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A common misconception is that weight loss is automatic and sustained, but in a follow-up study by Rubino et al., published in The Lancet Diabetes & Endocrinology (2022), participants who stopped semaglutide regained nearly two-thirds of the weight they had lost within one year

So the more useful question isn't whether the patches work it's what to do instead

Your best choice is the one you can repeat daily without nausea, because consistency protects muscle mass far more than perfect macros on paper

Garber AJ, Duncan TG, Goodman AM, Mills DJ, Rohlf JL Efficacy of metformin in type II diabetes: Results of a double-blind, placebo-controlled, dose-response trial