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In addition to digestive symptoms, GLP-1s can cause dizziness, increased heart rate, headaches, and injection-site symptoms such as itchiness or redness

Long-term weight loss from semaglutide often improves GERD severity despite initial heartburn during the first few weeks

This suggests that convenience of dosing does not fully offset tolerability challenges ( Table 1 offer a comparison between the oral based GLP-1 agents
