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Changes in Body Composition: As these medications alter how the body processes and stores fat and muscle, changes in body composition can occur, further affecting muscle strength

In clinical studies of GLP-1RA plus SGLT2i combination therapy, the safety profile of the combination therapy was consistent with those of the individual agents, with no unexpected findings [9]

Key Takeaways Diarrhea is a common gastrointestinal side effect of semaglutide, especially as the medication alters how quickly food moves through the digestive system

Without intervention, MASH carries a significant risk of progression to fibrosis and cirrhosis [2]
