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Knerr PJ, Mowery SA, Douros JD, Premdjee B, Hjollund KR, He Y, Kruse Hansen AM, Olsen AK, Perez-Tilve D, DiMarchi RD, et al

Evaluate concluded that pharma R&D spending is poised to grow significantly more slowly in the second half of the decade than it did in the first. It projects that the CAGR of more than 9% in 20162023 will shrink to below 3% between 20232030

Unfortunately, there is a paucity of biopsy-based pediatric MASLD studies, impeding an exact prescription of how much weight reduction should be achieved for histologic improvement in pediatric MASLD

These figures underscore a critical disconnect between clinical access, real-world adherence, and treatment outcomes with payer friction playing a central role