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Description
Circulating and tissue forms of the intestinal growth factor, glucagon-like peptide-2

Notably, 5-HT neurons in the DRN project to the arcuate nucleus of the hypothalamus (ARH), a region well known for its involvement in regulating food intake, energy homeostasis, and body weight [50, 51]

Mental health: Obesity is often associated with low self-esteem, depression, and anxiety due to societal stigma and body image concerns

When mast cells release inflammatory mediators near nerve endings, they can damage or kill neurons, worsening gut pain, dysmotility, and autonomic symptoms