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most abundant glutathione transferase in liver alpha 1 2 3 Frontiers Changes in Glutathione Content in
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C., & Tyagi, N

Describe the role of NADPH in detoxifying reactive oxygen species, and explain which cell types depend the most on the pentose phosphate pathway

Excessive alcohol metabolism in the liver produces ROS that can cross the blood-brain barrier, contributing to behavioral impairments associated with hangovers (Choi et al ., 2023

The nuclear transcription factor NEF2 serves as an inducer of SLC7A11 expression, while tumor suppressor genes TP53, BAP1, and BECN1 downregulate SLC7A11 expression [40,41,42]
