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When used in combination with other drugs for relapsed or refractory multiple myeloma, Darzalex is typically administered weekly during weeks 1 through 8, every 2 weeks during weeks 9 through 24, and then every 4 weeks until disease progression

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Systemic oral bioavailability for a 15-amino-acid unprotected peptide is expected to be very low based on general peptide pharmacokinetics
