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Simultaneously, it reduces oxidative stress in melanocytes, one of the key triggers for uneven pigmentation and dark spots (NIH)

These biases could potentially affect the reliability and validity of the findings

For example, vitamin D, especially its 1,25-(OH)2D form, is generally considered to be an antioxidant and its supplementation can reduce skeletal muscle, illustrating the potential for ROS generation to combat oxidative stress (120)

Thumb: Opposition, adduction, and abduction perpendicular to the palm
