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The genome of self-complementary adeno-associated viral vectors increases Toll-like receptor 9-dependent innate immune responses in the liver

The fast release of copper from CuHSA in the presence of His points to a different mechanism of demetallation and involvement of His in the rate-limiting step

Concurrently, HIV-1 icRNA activates macrophages and microglia [144, 171] and triggers pro-inflammatory responses in productively infected microglia [15]

This causes beneficial effects in overstimulated or damaged dopaminergic, serotonergic, and GABAergic systems
