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The unbalanced regulation of the glutathione synthesis coupled with the rapid and steady increase of glutathione abundance in the wheat tissue of the infested resistant plants suggested that the -glutamylcysteine synthetase might be either inhibited by a negative feedback from GSH, or it is not the rate-limiting enzyme in the glutathione synthetic pathway in wheat plants under our experimental conditions

2025 Jan 8:147:114001

Predictive value of oxidative stress biomarkers in drug-free schizophrenia and schizoaffective disorder

Several clinical studies have been conducted on the use of NAC as a potential therapeutic agent for insulin resistance and type 2 diabetes [28] (Table 1)