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The efficacy of anti-PD-1 monoclonal antibody nivolumab in advanced HCC has been assessed in a phase I/II study, which showed an objective response rate (ORR) of 20%, a disease control rate (DCR) of 64% and a median OS of 13.2 months (El-Khoueiry et al., 2017)

Peripheral immune system alterations, including increased cytokine levels and immune cell infiltration, suggest a systemic component to the inflammatory process in HD [4749]

Diese hydrolysierten Kollagenprparate werden oral eingenommen und sollen die Knorpel- und Sehnenstruktur durch Bereitstellung von Bausteinen oder durch stimulierende Effekte auf die extrazellulre Matrix untersttzen

Echinacea, revered for its immunomodulatory effects, can enhance the bodys defense mechanisms