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However, neither the A-ring transformation nor the dimerization mechanisms have been explored thus far

This subsequently impedes tumorigenicity and invasiveness while enhancing chemosensitivity in PDAC, particularly in CD133 + CSCs [76, 86]

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Additionally, since the longer chain humectants will sit on the top of the skin and bind reversibly to smaller humectants (via whats called hydrogen bonding), the smaller humectants will gradually absorb into the skin over a longer period of time, like an extended release humectant system, so the plumping and hydration effects last longer