mitochondrial l-carnitine shuttle pathway The carnitine links metabolism to histone acetylation and lipogenesis Carnitine Shuttle - an overview

Carnitine plays crucial role in energy production - esp for the heart, fueling mitochondria (cell furnaces)

The CSF concentrations paralleled those in plasma, suggesting that ALC easily crosses the blood-brain barrier.

It might take as short as a few day after cessation of carnitine, cardiac arrhythmia and cardiac arrest might come suddenly leading to fatal outcome.23,24 On the other hand, it is uncertain if asymptomatic carrier (with one mutation) should be treated with carnitine

Unfortunately, at the present time one cannot be completely certain that the hydroxylation of hydroxyamphetamine in vivo is accomplished by the same enzyme which converts dopamine to noradrenaline