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Here we have identified that depletion of -ketoglutarate (KG) sensitizes HR-proficient cells to DNA-damaging agents by metabolic regulation of histone acetylation
This is detrimental not only to sperm health but to other bodily processes that rely on calcium, for example, blood clotting
Mardanshahi T, Rezaei N, Zare Z, Shafaroudi MM, Mohammadi H
Activating PPAR under specific circumstances accelerates adipocyte maturation, whereas the inability of PPAR to function properly hampers efficient embryonic cell differentiation into adipocytes
