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Rhonda Patrick: And I made a video on this years ago, 2016 maybe, and I think I have the references on there to exact amounts

In vivo studies in iron-deficient mice confirm this: erythrocytes exhibit increased PS exposure, reduced glutathione (GSH) levels, and accelerated clearance, with these defects reversed by iron repletion ( 2+ homeostasis: non-selective cation channels in the RBC membranecritical for Ca 2+ entryare upregulated by iron depletion, possibly via ROS-mediated gating

These factors suggest that the pain reduction is likely a result of both physiological changes and enhanced psychological well-being