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half of them were excreted in significantly higher quantities in smokers than in non-smokers [258]

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If not for thiolredox maintenance, GSH might otherwise be essential by its requirement, together with the mitochondrial innermembrane ABC transporter Atm1 and the intermembrane space Erv1 thiol oxidase, for maturation of cytoplasmic ironsulphur cluster (ISC) by the cytosolic ISC assembly (CIA) system (Kispal et al , 1999

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