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35,36 Lipoteichoic acid (LTA) is a major component of the cell wall in Gram-positive bacteria, and the LTA synthase ( BC3765 ) is upregulated in 48 h and 72 h aged biofilms

This implies that the increase in Cys2 stimulated Met synthesis

Therefore, CBFD is considered to have a dual function as not only a -4-hydroxylase/3,4-desaturase to the -end group but also as a C3-hydroxylase of the C4-keto--end group [264] (Figure 11)
