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Keerthana CK, et al

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The concept of blocking the IGF1 receptor in cancer is based on sound experimental animal data showing that targeting this receptor results in tumour cell apoptosis, the principle therapeutic hurdle in cancer

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doi: 10.1016/j.pain.2005.02.009

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[2] One of the limiting factors of an enzymatic reaction is the frequency of collisions between enzymes and substrates

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