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Said, G

Targeting extracellular matrix stiffness to attenuate disease: from molecular mechanisms to clinical trials

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Alternatively, two of the substituents on adjacent atoms of aryl or heteroaryl ring may optionally be replaced with a substituent of the formula (CRR) s X(CR) d , where s and d are independently integers of from 0 to 3, and X is O, NR, S, S(O), S(O) 2 , or S(O) 2 NR
