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Methodology Approach to literature review This narrative review employs a qualitative and exploratory methodology, amalgamating diverse literature sources to offer a comprehensive elucidation of Ashwagandhas efficacy in augmenting physical performance and overall health

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In this review, we summarize the regulation of the System X c /GSH/GPX4 axis, a major antioxidant system in ferroptosis, and its potential role in drug-resistant solid tumors therapy, and also conclude with a summary of drugs, compounds and nanoparticles targeting this axis that have been studied in recent years