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While ROS scavenging may alleviate intestinal inflammation, it is essential to detect and preserve the diurnal rhythms of ROS during antioxidant therapies, thereby avoiding disruption of the rhythmic oscillation of gut microbiota
Low ROS levels promote oncogenic signaling transduction, while high ROS levels induce cellular damage and death [384]
Three of the 10 most common clozapine side effects are cardiac: tachycardia, hypotension, and hypertension ( Figure 1 )
