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Hericium erinaceus inhibits TNF--induced angiogenesis and ROS generation through suppression of MMP-9/NF-B signaling and activation of Nrf2-mediated antioxidant genes in human EA.hy926 endothelial cells
Statins and other cholesterol-modifying agents can decrease cholesterol turnover and dampen the excessive production of oxysterols
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In the CNS, melatonin is metabolized mainly by the enzyme indoleamine 2,3-dioxygenase (IDO), giving rise to the metabolite N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK), which is subsequently transformed into N-acetyl-5-methoxykynuramine (AMK) [1,6]
