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These findings support GSH as a potent adjuvant for improving ovarian tissue vitrification outcomes and warrant further translational evaluation in fertility preservation protocols

The last effect is important since it avoids any artificial reduction of GSSG to GSH during sample handling as the consequence of the shift to the right of the equilibrium (1): Therefore, the reaction of NEM with SH groups is so rapid and effective that any perturbation of the GSH-GSSG equilibrium is avoided

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