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Especially since the enzymatic assays are costly, laborious and only performed in a limited number of centers

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Platelet activation was studied by dosing sCD40L

However, even in the absence of these phosphatases, levels of PI(4,5)P 2 in endosomes are not severely elevated in many cell types, indicating that there are other mechanisms for suppressing PI(4,5)P 2 accumulation in endosomes
