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Pegaptanib, a VEGF antagonist with a three-dimensionally structured aptamer, was initially used to inhibit pathological neovascularization and reverse disease progression but was later removed from the market

Song X, Jiao H, Zhao J, Wang X, Lin H (2019) Ghrelin serves as a signal of energy utilization and is involved in maintaining energy homeostasis in broilers

CO2 laser resurfacing is a powerful treatment for improving the appearance of the skin

However, the multi-targeted mechanism of action of YNBY suggests the need to analyze multiple aspects of the effects of a drug, including at molecular, cellular, and overall levels