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Differential and overlapping effects of 20,23(OH)2D3 and 1,25(OH)2D3 on gene expression in human epidermal keratinocytes: identification of AhR as an alternative receptor for 20,23(OH)2D3

When applied topically, it can help to reduce oxidative stress on the skin, which may help to improve skin health and appearance

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Its expression is significantly increased in lung adenocarcinoma, downregulated in gastric and colorectal cancers and altered during the differentiation of pluripotent embryonic stem cells ( CHAC2 was upregulated in a model of APAP-induced hepatic damage following treatment with naringin (Zhai et al., 2022)