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Our previous work in human macrophages indicates that HIV blocks the formation of the apoptosome and that in surviving cells Bim, a highly apoptotic protein, is recruited to the mitochondria without resulting in apoptosis 23 , suggesting that in HIV surviving cells, mitochondrial function is compromised

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46 In addition to the patient's unique clinical presentation, they may present with concomitant musculoskeletal deficits

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