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Martinelli et al

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The structure of the kumamolisin-As enzyme from the acidophilic bacterium Alicyclobacillus sendaiensis provided a starting point for engineering a gluten-degrading enzyme that is active in the acidic conditions of the stomach

Retatrutide simultaneously activates GLP-1, GIP, and glucagon receptors, distinguishing it from licensed agents such as semaglutide or tirzepatide
