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Akpinar, I

however, translating it into the real world for skin lightning is complex

In this process, substrate-derived electrons are transferred to molecular oxygen with formation of superoxide anions (Byrne et al., 2009) and hydrogen peroxides (Haensch et al., 2006)

68 Of note, the BNIP3/NIX pathway was specifically up-regulated when mitochondrial oxidative stress was generated in the hypoxic environment to further induce mitophagy
