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We also found that the T-allele of this SNP was associated with higher urine-Hg levels (Table 3), which is in agreement with previous reports on mining settings 6,29

This research was funded by Consejo Nacional de Ciencia y Tecnologa (CONACYT) Mxico, Grants Numbers A1-S-7495, by Programa de Apoyo a Proyectos de Investigacin e Innovacin Tecnolgica (PAPIIT), Grant Numbers IN202219 and IN200922 of the Universidad Nacional Autnoma de Mxico (UNAM), and by Programa de Apoyo a la Investigacin y el Posgrado (PAIP), Grant Number 5000-9105

Proline DCs are classic innate immune cells, and studies have shown that proline modulates innate immunity in Caenorhabditis elegans by balancing redox homeostasis and activating the key transcription factor SKN-1 associated with pathogen defense (115)