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Its main effects include: Increasing lipolysis (fat breakdown) Reducing lipogenesis (fat storage) Improving fat metabolism signaling Doing so without affecting muscle, bone, or glucose regulation Importantly: It does not stimulate growth hormone release It does not rely on pituitary feedback loops It does not act on central appetite pathways This is why it has such a clean safety profile

Reduced caloric intake from tirzepatide plus enhanced fat mobilization from AOD 9604 creates a significant metabolic shift that the body needs time to adapt to

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GLUT4, which is primarily located in striated muscle (skeletal and cardiac) and adipose tissue, plays a major role in regulating glucose uptake and overall energy balance