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Adverse effects of tobacco cigarettes are usually attributed to the vast number of chemicals found in burned tobacco leaves and smoke, as well as nicotine, which is known to impact cardiovascular and endocrine systems [77, 82]
As a result, the livers ability to produce the master antioxidant, glutathione, is reduced leading to oxidative damage, fatigue, and premature aging

J Hematol Oncol 10(1):36

Montresor, A
