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Endocrine 66(3):542550

Mongersen exhibited good efficacy and safety for the treatment of CD in one phase 1 and three phase 2 clinical trials [155,156,157,158], but its development was suspended due to a lack of efficacy in phase 3 clinical trials

Severe niacin deficiency, known as pellagra, has been historically associated with poverty and consumption of a diet predominantly based on corn, which is low in bioavailable niacin (25, 26)