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Under other circumstances, however, hyperinsulinemia is considered as pathological and it is a hallmark of prediabetes 88 , correlated to elevated risks of overweight and obesity in ordinary individuals 89,90

Glutathione Content For the glutathione experiments, an additional subset of hearts (n = 5) were perfused under normoxic conditions without diamide to serve as a time control group

Targeting PGAM5 in tumor cells reduces mitochondrial DNA stress and suppresses M2 polarization via the TLR9/NF-B/CCL2 axis, significantly improving the efficacy of immunotherapy in liver cancer (279)

Regulation of ferroptosis Regulation of ferroptosis mediated by intervention in PUFAs levels PUFAs refer to polyunsaturated fatty acids that contain two or more double bonds within their molecular structure