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Description
Rapid glutamate release in the mediobasal hypothalamus accompanies feeding and is exaggerated by an obesogenic food Mol Metab 2 2: 116-22

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CACT acetylation compromises its activity, causing a decrease in its transport function

Diagnosis To diagnose CHE, the patient must have 1) a disease that can lead to CHE, such as liver cirrhosis or a portosystemic shunt, 2) no other neurological disease, 3) no neurological manifestation such as disorientation or asterixis, and 4) abnormal cognitive or neurophysiologic functioning
