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10.1080/09168451.2018.1543015 26 BaiL.HanX.KeeH

Increasing NAD + levels by supplementing NR in mouse tissues and mammalian cells activates SIRT1 and SIRT3, which ultimately leads to increased oxidative metabolism and prevents metabolic abnormalities induced by HFD

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Thus, the presence of protozoa within intestinal tissue layers may enhance the immune system and prevent colon cancer, and the loss of these organisms could lead to a higher incidence of colon cancer